Cargando…
Network location and clustering of genetic mutations determine chronicity in a stylized model of genetic diseases
In a highly simplified view, a disease can be seen as the phenotype emerging from the interplay of genetic predisposition and fluctuating environmental stimuli. We formalize this situation in a minimal model, where a network (representing cellular regulation) serves as an interface between an input...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675813/ https://www.ncbi.nlm.nih.gov/pubmed/36402799 http://dx.doi.org/10.1038/s41598-022-23775-9 |