Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer

DNA damaging agents are a mainstay of standard chemotherapy for ovarian cancer. Unfortunately, resistance to such DNA damaging agents frequently develops, often due to increased activity of DNA repair pathways. Sideroflexin 4 (SFXN4) is a little-studied inner mitochondrial membrane protein. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales: Tesfay, Lia, Paul, Bibbin T., Hegde, Poornima, Brewer, Molly, Habbani, Samrin, Jellison, Evan, Moore, Timothy, Wu, Hao, Torti, Suzy V., Torti, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675821/
https://www.ncbi.nlm.nih.gov/pubmed/36402786
http://dx.doi.org/10.1038/s41598-022-24391-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675821/
https://www.ncbi.nlm.nih.gov/pubmed/36402786
http://dx.doi.org/10.1038/s41598-022-24391-3

Ejemplares similares