Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ mice

Muscle repair in dysferlinopathies is defective. Although macrophage (Mø)-rich infiltrates are prominent in damaged skeletal muscles of patients with dysferlinopathy, the contribution of the immune system to the disease pathology remains to be fully explored. Numbers of both pro-inflammatory M1 Mø a...

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Detalles Bibliográficos
Autores principales: Farini, A., Tripodi, L., Villa, C., Napolitano, F., Strati, F., Molinaro, D., Facciotti, F., Cassani, B., Torrente, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675822/
https://www.ncbi.nlm.nih.gov/pubmed/36402750
http://dx.doi.org/10.1038/s41419-022-05416-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675822/
https://www.ncbi.nlm.nih.gov/pubmed/36402750
http://dx.doi.org/10.1038/s41419-022-05416-1

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