Pulmonary cancers across different histotypes share hybrid tuft cell/ionocyte-like molecular features and potentially druggable vulnerabilities

Tuft cells are chemosensory epithelial cells in the respiratory tract and several other organs. Recent studies revealed tuft cell-like gene expression signatures in some pulmonary adenocarcinomas, squamous cell carcinomas (SQCC), small cell carcinomas (SCLC), and large cell neuroendocrine carcinomas...

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Detalles Bibliográficos
Autores principales: Yamada, Yosuke, Belharazem-Vitacolonnna, Djeda, Bohnenberger, Hanibal, Weiß, Christel, Matsui, Naoko, Kriegsmann, Mark, Kriegsmann, Katharina, Sinn, Peter, Simon-Keller, Katja, Hamilton, Gerhard, Graeter, Thomas, Preissler, Gerhard, Ott, German, Schölch, Sebastian, Nakajima, Naoki, Yoshizawa, Akihiko, Haga, Hironori, Date, Hiroshi, Thomas, Roman K., Petrini, Iacopo, Giaccone, Giuseppe, Ströbel, Philipp, Marx, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675833/
https://www.ncbi.nlm.nih.gov/pubmed/36402755
http://dx.doi.org/10.1038/s41419-022-05428-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675833/
https://www.ncbi.nlm.nih.gov/pubmed/36402755
http://dx.doi.org/10.1038/s41419-022-05428-x

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