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The diminution and modulation role of water-soluble gallic acid-carboxymethyl chitosan conjugates against the induced nephrotoxicity with cisplatin

The toxicity of cisplatin (CDDP) toward the renal tubules and its severe effects on the proximal tubules limits its further use in cancer therapy. The current study was undertaken to evaluate the protective effects of gallic acid-grafted O-carboxymethyl chitosan (GA@CMCS) against nephrotoxicity indu...

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Detalles Bibliográficos
Autores principales: Hafez, Hani S., Kotb, Ebtesam S., El-Khayat, Zakaria, Elshaarawy, Reda F. M., Serag, Waleed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675851/
https://www.ncbi.nlm.nih.gov/pubmed/36402822
http://dx.doi.org/10.1038/s41598-022-21681-8