Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome

The correct development and activity of neurons and glial cells is necessary to establish proper brain connectivity. DYRK1A encodes a protein kinase involved in the neuropathology associated with Down syndrome that influences neurogenesis and the morphological differentiation of neurons. DYRK1A loss...

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Detalles Bibliográficos
Autores principales: Pijuan, Isabel, Balducci, Elisa, Soto-Sánchez, Cristina, Fernández, Eduardo, Barallobre, María José, Arbonés, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675854/
https://www.ncbi.nlm.nih.gov/pubmed/36402907
http://dx.doi.org/10.1038/s41598-022-24284-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675854/
https://www.ncbi.nlm.nih.gov/pubmed/36402907
http://dx.doi.org/10.1038/s41598-022-24284-5

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