Cargando…

Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome

The correct development and activity of neurons and glial cells is necessary to establish proper brain connectivity. DYRK1A encodes a protein kinase involved in the neuropathology associated with Down syndrome that influences neurogenesis and the morphological differentiation of neurons. DYRK1A loss...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pijuan, Isabel, Balducci, Elisa, Soto-Sánchez, Cristina, Fernández, Eduardo, Barallobre, María José, Arbonés, Maria L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675854/ https://www.ncbi.nlm.nih.gov/pubmed/36402907 http://dx.doi.org/10.1038/s41598-022-24284-5

Ejemplares similares

Retinal Macroglial Responses in Health and Disease
por: de Hoz, Rosa, et al.
Publicado: (2016)

DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome
por: Najas, Sònia, et al.
Publicado: (2015)

Macroglial diversity: white and grey areas and relevance to remyelination
por: Werkman, Inge L., et al.
Publicado: (2020)

DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease
por: Barallobre, M J, et al.
Publicado: (2014)

DYRK1A pathogenic variants in two patients with syndromic intellectual disability and a review of the literature
por: Meissner, Laura E., et al.
Publicado: (2020)

The Effect of Plasma Rich in Growth Factors on Microglial Migration, Macroglial Gliosis and Proliferation, and Neuronal Survival
por: Ruzafa, Noelia, et al.
Publicado: (2021)

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract
por: Blackburn, Alexandria T.M., et al.
Publicado: (2019)

Case report of novel DYRK1A mutations in 2 individuals with syndromic intellectual disability and a review of the literature
por: Luco, Stephanie M., et al.
Publicado: (2016)

A De Novo Mutation in DYRK1A Causes Syndromic Intellectual Disability: A Chinese Case Report
por: Qiao, Fengchang, et al.
Publicado: (2019)

New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome
por: Park, Joongkyu, et al.
Publicado: (2013)

Prenatal Neuropathologies in Autism Spectrum Disorder and Intellectual Disability: The Gestation of a Comprehensive Zebrafish Model
por: Kozol, Robert A.
Publicado: (2018)

One-carbon cycle alterations induced by Dyrk1a dosage
por: Delabar, Jean-Maurice, et al.
Publicado: (2014)

DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release
por: Lee, Ye Hyung, et al.
Publicado: (2022)

Risperidone in the treatment of conduct disorder in preschool children without intellectual disability
por: Ercan, Eyup S, et al.
Publicado: (2011)

Impaired Spatial Learning Strategies and Novel Object Recognition in Mice Haploinsufficient for the Dual Specificity Tyrosine-Regulated Kinase-1A (Dyrk1A)
por: Arqué, Glòria, et al.
Publicado: (2008)

Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A
por: Guedj, Fayçal, et al.
Publicado: (2009)

"Familial" versus "sporadic" intellectual disability: contribution of subtelomeric rearrangements
por: Rafati, Maryam, et al.
Publicado: (2012)

Overexpression of Dyrk1A Is Implicated in Several Cognitive, Electrophysiological and Neuromorphological Alterations Found in a Mouse Model of Down Syndrome
por: García-Cerro, Susana, et al.
Publicado: (2014)

Variants in NGLY1 lead to intellectual disability, myoclonus epilepsy, sensorimotor axonal polyneuropathy and mitochondrial dysfunction
por: Panneman, Daan M., et al.
Publicado: (2020)

Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism
por: Widowati, Esti Wahyu, et al.
Publicado: (2018)

Mortality in individuals with intellectual disabilities in Finland
por: Arvio, Maria, et al.
Publicado: (2016)

Plasma DYRK1A as a novel risk factor for Alzheimer's disease
por: Janel, N, et al.
Publicado: (2014)

Intellectual disabilities and yoga
por: Singh, Satendra
Publicado: (2013)

Anesthesia for intellectually disabled
por: Chaudhary, Kapil, et al.
Publicado: (2017)

Intellectual Disability and Parenthood
por: Kandel, Isack, et al.
Publicado: (2005)

Intellectual disability and antipsychotics
por: Iñiguez, I. Cuevas, et al.
Publicado: (2021)

Nymphomania with intellectual disability
por: Sharma, Mini, et al.
Publicado: (2022)

The Genetics of Intellectual Disability
por: Jansen, Sandra, et al.
Publicado: (2023)

A clinical primer on intellectual disability
por: Patel, Dilip R., et al.
Publicado: (2020)

Clinical guidelines contribute to the health inequities experienced by individuals with intellectual disabilities
por: Mizen, Lindsay AM, et al.
Publicado: (2012)

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability
por: Singh, Tarjinder, et al.
Publicado: (2017)

Model of Intellectual Disability and the Relationship of Attitudes Towards the Sexuality of Persons with an Intellectual Disability
por: Parchomiuk, Monika
Publicado: (2012)

Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland
por: Kurki, Mitja I., et al.
Publicado: (2019)

Caregiving, intellectual disability, and dementia: Report of the Summit Workgroup on Caregiving and Intellectual and Developmental Disabilities
por: Heller, Tamar, et al.
Publicado: (2018)

Dental treatment under general anesthesia in an intellectually disabled child with intellectually disabled parents
por: Han, Jeong-Hwa, et al.
Publicado: (2016)

Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer’s disease
por: Janel, N, et al.
Publicado: (2017)

Intellectual disability in patients with epilepsy with eyelid myoclonias
por: Arvio, Maria, et al.
Publicado: (2018)

"Familial" versus "Sporadic" intellectual disability: contribution of common microdeletion and microduplication syndromes
por: Rafati, Maryam, et al.
Publicado: (2012)

The Contributions of Memory and Vocabulary to Non-Verbal Ability Scores in Adolescents with Intellectual Disability
por: Mungkhetklang, Chantanee, et al.
Publicado: (2016)

Decoding Abilities in Adolescents with Intellectual Disabilities: The Contribution of Cognition, Language, and Home Literacy
por: Nilsson, Karin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9j3g7aku27nrlecoom6spqv3es