3’UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension

Pulmonary hypertension (PH) comprises a diverse group of disorders that share a common pathway of pulmonary vascular remodeling leading to right ventricular failure. Development of anti-remodeling strategies is an emerging frontier in PH therapeutics that requires a greater understanding of the inte...

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Detalles Bibliográficos
Autores principales: Tseng, Victor, Collum, Scott D., Allawzi, Ayed, Crotty, Kathryn, Yeligar, Samantha, Trammell, Aaron, Smith, M. Ryan, Kang, Bum-Yong, Sutliff, Roy L., Ingram, Jennifer L., Jyothula, Soma S.S.K., Thandavarayan, Rajarajan A., Huang, Howard J., Nozik, Eva S., Wagner, Eric J., Hart, C. Michael, Karmouty-Quintana, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676077/
https://www.ncbi.nlm.nih.gov/pubmed/35671866
http://dx.doi.org/10.1016/j.matbio.2022.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676077/
https://www.ncbi.nlm.nih.gov/pubmed/35671866
http://dx.doi.org/10.1016/j.matbio.2022.06.001

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