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Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration

Stem cell transplantation has been proved a promising therapeutic instrument in intervertebral disc degeneration (IVDD). However, the elevation of oxidative stress in the degenerated region impairs the efficiency of mesenchymal stem cells (BMSCs) transplantation treatment via exaggeration of mitocho...

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Detalles Bibliográficos
Autores principales: Sun, Junyuan, Yang, Fei, Wang, Lianlei, Yu, Haichao, Yang, Zhijie, Wei, Jingjing, Vasilev, Krasimir, Zhang, Xuesong, Liu, Xinyu, Zhao, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676151/
https://www.ncbi.nlm.nih.gov/pubmed/36439087
http://dx.doi.org/10.1016/j.bioactmat.2022.10.019