Cargando…

Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration

Stem cell transplantation has been proved a promising therapeutic instrument in intervertebral disc degeneration (IVDD). However, the elevation of oxidative stress in the degenerated region impairs the efficiency of mesenchymal stem cells (BMSCs) transplantation treatment via exaggeration of mitocho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Junyuan, Yang, Fei, Wang, Lianlei, Yu, Haichao, Yang, Zhijie, Wei, Jingjing, Vasilev, Krasimir, Zhang, Xuesong, Liu, Xinyu, Zhao, Yunpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676151/ https://www.ncbi.nlm.nih.gov/pubmed/36439087 http://dx.doi.org/10.1016/j.bioactmat.2022.10.019

Ejemplares similares

ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration
por: Feng, Chencheng, et al.
Publicado: (2017)

Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation
por: Zhao, Yunpeng, et al.
Publicado: (2020)

Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway
por: Yu, Haichao, et al.
Publicado: (2021)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Hydroxytyrosol Ameliorates Intervertebral Disc Degeneration and Neuropathic Pain by Reducing Oxidative Stress and Inflammation
por: Yu, Haichao, et al.
Publicado: (2022)

The Proteolysis of ECM in Intervertebral Disc Degeneration
por: Liang, Huaizhen, et al.
Publicado: (2022)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Targeting Ferroptosis Holds Potential for Intervertebral Disc Degeneration Therapy
por: Chen, Jiaxing, et al.
Publicado: (2022)

Propionibacterium acnes Accelerates Intervertebral Disc Degeneration by Inducing Pyroptosis of Nucleus Pulposus Cells via the ROS-NLRP3 Pathway
por: Tang, Guoqing, et al.
Publicado: (2021)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Injectable kartogenin and apocynin loaded micelle enhances the alleviation of intervertebral disc degeneration by adipose-derived stem cell
por: Yu, Chao, et al.
Publicado: (2021)

Mitochondrial quality control in intervertebral disc degeneration
por: Song, Yu, et al.
Publicado: (2021)

The Role of Oxidative Stress in Intervertebral Disc Degeneration
por: Cao, Guoshuai, et al.
Publicado: (2022)

Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
por: Feng, Chencheng, et al.
Publicado: (2016)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

The Role of Adipokines in Intervertebral Disc Degeneration
por: Sharma, Anirudh
Publicado: (2018)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Genetic Therapy for Intervertebral Disc Degeneration
por: Roh, Eun Ji, et al.
Publicado: (2021)

Cervical intervertebral disc degeneration and dizziness
por: Liu, Tang-Hua, et al.
Publicado: (2021)

The role of ferroptosis in intervertebral disc degeneration
por: Fan, Chunyang, et al.
Publicado: (2023)

Role of Necroptosis in Intervertebral Disc Degeneration
por: Khaleque, Md Abdul, et al.
Publicado: (2023)

Role of microRNAs in intervertebral disc degeneration (Review)
por: Yang, Fengguang, et al.
Publicado: (2021)

Regulatory Effect of Inflammatory Mediators in Intervertebral Disc Degeneration
por: Li, Zhangfu, et al.
Publicado: (2023)

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
por: Millward-Sadler, S Jane, et al.
Publicado: (2009)

Application of stem cells in the repair of intervertebral disc degeneration
por: Zhang, Wentao, et al.
Publicado: (2022)

The potential mechanisms and application prospects of non-coding RNAs in intervertebral disc degeneration
por: Jiang, Chao, et al.
Publicado: (2022)

Bovine explant model of degeneration of the intervertebral disc
por: Roberts, Sally, et al.
Publicado: (2008)

Intervertebral disc degeneration: biological and biomechanical factors
por: An, Howard S., et al.
Publicado: (2006)

Stem cell horizons in intervertebral disc degeneration
por: Ciacci, Joseph, et al.
Publicado: (2009)

Notochord Cells in Intervertebral Disc Development and Degeneration
por: McCann, Matthew R., et al.
Publicado: (2016)

Inflammatory profiles in canine intervertebral disc degeneration
por: Willems, Nicole, et al.
Publicado: (2016)

Effects of bone cement on intervertebral disc degeneration
por: ZHAO, HUI, et al.
Publicado: (2014)

Current Understanding of the Genetics of Intervertebral Disc Degeneration
por: Dickinson, Peter J., et al.
Publicado: (2020)

Adrenoceptor Expression during Intervertebral Disc Degeneration
por: Kupka, Johannes, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4ecpupm7d2hr4d1i841v0c10u9