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Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq

Thousands of RNA-binding proteins orchestrate RNA processing and altered protein-RNA interactions frequently lead to disease. Here, we present experimental and computational analysis pipelines of fractionated eCLIP-seq (freCLIP-seq), a modification of enhanced UV-crosslinking and RNA immunoprecipita...

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Detalles Bibliográficos
Autores principales: Biancon, Giulia, Busarello, Emma, Joshi, Poorval, Lesch, Bluma J., Halene, Stephanie, Tebaldi, Toma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676202/
https://www.ncbi.nlm.nih.gov/pubmed/36595959
http://dx.doi.org/10.1016/j.xpro.2022.101823