Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fibrosis in mice

Exposure to high concentrations of hydrochloric acid (HCl) can lead to severe acute and chronic lung injury. In the aftermath of accidental spills, victims may be treated for the acute symptoms, but the chronic injury is often overlooked. We have developed a mouse model of acute and chronic lung inj...

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Detalles Bibliográficos
Autores principales: Solopov, Pavel A., Colunga Biancatelli, Ruben Manuel Luciano, Dimitropolou, Christiana, Day, Tierney, Catravas, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676235/
https://www.ncbi.nlm.nih.gov/pubmed/36419627
http://dx.doi.org/10.3389/fphar.2022.1034464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676235/
https://www.ncbi.nlm.nih.gov/pubmed/36419627
http://dx.doi.org/10.3389/fphar.2022.1034464

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