Prediction of homologous recombination deficiency from cancer gene expression data

OBJECTIVE: Homologous recombination deficiency (HRD) is the main mechanism of tumorigenesis in some cancers. HRD causes abnormal double-strand break repair, resulting in genomic scars. Some scoring HRD tests have been approved as companion diagnostics of polyadenosine diphosphate-ribose polymerase (...

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Detalles Bibliográficos
Autores principales: Kang, Jun, Lee, Jieun, Lee, Ahwon, Lee, Youn Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676333/
https://www.ncbi.nlm.nih.gov/pubmed/36380518
http://dx.doi.org/10.1177/03000605221133655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676333/
https://www.ncbi.nlm.nih.gov/pubmed/36380518
http://dx.doi.org/10.1177/03000605221133655

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