Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency

Cardiomyocytes differentiated from human induced Pluripotent Stem Cells (hiPSC- CMs) are a unique source for modelling inherited cardiomyopathies. In particular, the possibility of observing maturation processes in a simple culture dish opens novel perspectives in the study of early-disease defects...

Descripción completa

Detalles Bibliográficos
Autores principales: Pioner, Josè Manuel, Santini, Lorenzo, Palandri, Chiara, Langione, Marianna, Grandinetti, Bruno, Querceto, Silvia, Martella, Daniele, Mazzantini, Costanza, Scellini, Beatrice, Giammarino, Lucrezia, Lupi, Flavia, Mazzarotto, Francesco, Gowran, Aoife, Rovina, Davide, Santoro, Rosaria, Pompilio, Giulio, Tesi, Chiara, Parmeggiani, Camilla, Regnier, Michael, Cerbai, Elisabetta, Mack, David L., Poggesi, Corrado, Ferrantini, Cecilia, Coppini, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676373/
https://www.ncbi.nlm.nih.gov/pubmed/36419836
http://dx.doi.org/10.3389/fphys.2022.1030920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676373/
https://www.ncbi.nlm.nih.gov/pubmed/36419836
http://dx.doi.org/10.3389/fphys.2022.1030920

Ejemplares similares