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Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency
Cardiomyocytes differentiated from human induced Pluripotent Stem Cells (hiPSC- CMs) are a unique source for modelling inherited cardiomyopathies. In particular, the possibility of observing maturation processes in a simple culture dish opens novel perspectives in the study of early-disease defects...
Autores principales: | Pioner, Josè Manuel, Santini, Lorenzo, Palandri, Chiara, Langione, Marianna, Grandinetti, Bruno, Querceto, Silvia, Martella, Daniele, Mazzantini, Costanza, Scellini, Beatrice, Giammarino, Lucrezia, Lupi, Flavia, Mazzarotto, Francesco, Gowran, Aoife, Rovina, Davide, Santoro, Rosaria, Pompilio, Giulio, Tesi, Chiara, Parmeggiani, Camilla, Regnier, Michael, Cerbai, Elisabetta, Mack, David L., Poggesi, Corrado, Ferrantini, Cecilia, Coppini, Raffaele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676373/ https://www.ncbi.nlm.nih.gov/pubmed/36419836 http://dx.doi.org/10.3389/fphys.2022.1030920 |
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