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Shc Is Implicated in Calreticulin-Mediated Sterile Inflammation in Alcoholic Hepatitis

BACKGROUND & AIMS: Src homology and collagen (Shc) proteins are major adapters to extracellular signals, however, the regulatory role of Shc isoforms in sterile inflammatory responses in alcoholic hepatitis (AH) has not been fully investigated. We hypothesized that in an isoform-specific manner...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Jiang, Joy X., Fan, Weiguo, Fish, Sarah R., Das, Suvarthi, Gupta, Parul, Mozes, Gergely, Vancza, Lorand, Sarkar, Sutapa, Kunimoto, Koshi, Chen, Dongning, Park, Hyesuk, Clemens, Dahn, Tomilov, Alexey, Cortopassi, Gino, Török, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676381/
https://www.ncbi.nlm.nih.gov/pubmed/36122677
http://dx.doi.org/10.1016/j.jcmgh.2022.09.005