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The influence of three-dimensional structure on naïve T cell homeostasis and aging

A breakdown in cellular homeostasis is thought to drive naïve T cell aging, however the link between naïve T cell homeostasis and aging in humans is poorly understood. To better address this, we developed a lymphoid organoid system that maintains resting naïve T cells for more than 2 weeks, in conju...

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Detalles Bibliográficos
Autores principales: Lambert, Simon, Cao, Wenqiang, Zhang, Huimin, Colville, Alex, Liu, Jie-Yu, Weyand, Cornelia M., Goronzy, Jorg J., Gustafson, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676450/
https://www.ncbi.nlm.nih.gov/pubmed/36419548
http://dx.doi.org/10.3389/fragi.2022.1045648