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Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells

N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is aberrant. Neu5Gc has been observed in human can...

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Detalles Bibliográficos
Autores principales:	Yang, Wenqian, Jiang, Yuan, Guo, Qulian, Tian, Zhixin, Cheng, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676485/ https://www.ncbi.nlm.nih.gov/pubmed/36419929 http://dx.doi.org/10.3389/fmolb.2022.1047672

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