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Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells

N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is aberrant. Neu5Gc has been observed in human can...

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Detalles Bibliográficos
Autores principales: Yang, Wenqian, Jiang, Yuan, Guo, Qulian, Tian, Zhixin, Cheng, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676485/
https://www.ncbi.nlm.nih.gov/pubmed/36419929
http://dx.doi.org/10.3389/fmolb.2022.1047672