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Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-2

Multiple SARS-CoV-2 vaccine candidates have been approved for use and have had a major impact on the COVID-19 pandemic. There remains, however, a significant need for vaccines that are safe, easily transportable and protective against infection, as well as disease. Mucosal vaccination is favored for...

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Detalles Bibliográficos
Autores principales: Stewart, Erica L., Counoupas, Claudio, Johansen, Matt D., Nguyen, Duc H., Miemczyk, Stefan, Hansbro, Nicole G., Ferrell, Kia C., Ashhurst, Anneliese, Alca, Sibel, Ashley, Caroline, Steain, Megan, Britton, Warwick J., Hansbro, Philip M., Petrovsky, Nikolai, Triccas, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676795/
https://www.ncbi.nlm.nih.gov/pubmed/36411332
http://dx.doi.org/10.1038/s41385-022-00578-9