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Case report: EML4::NTRK3 gene fusion in a patient with metastatic lung adenocarcinoma successfully treated with entrectinib

Rearrangements involving the neurotrophin kinase (NTRK) genes NTRK1, NTRK2 and NTRK3 with different fusion partners have been observed in both adult and pediatric solid tumors. Larotrectinib and entrectinib have been the first tumor-agnostic compounds approved for the treatment of NTRK fusion-positi...

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Detalles Bibliográficos
Autores principales: Lazzari, Chiara, Pecciarini, Lorenza, Doglioni, Claudio, Pedica, Federica, Gajate, Ana Maria Samanes, Bulotta, Alessandra, Gregorc, Vanesa, Cangi, Maria Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676932/
https://www.ncbi.nlm.nih.gov/pubmed/36419889
http://dx.doi.org/10.3389/fonc.2022.1038774