Loss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice

The type 2 Ca(2+)-dependent activator protein for secretion (CAPS2/CADPS2) regulates dense-core vesicle trafficking and exocytosis and is involved in the regulated release of catecholamines, peptidergic hormones, and neuromodulators. CAPS2 is expressed in the pancreatic exocrine acinar cells that pr...

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Detalles Bibliográficos
Autores principales: Sato, Yotaroh, Tsuyusaki, Miho, Takahashi-Iwanaga, Hiromi, Fujisawa, Rena, Masamune, Atsushi, Hamada, Shin, Matsumoto, Ryotaro, Tanaka, Yu, Kakuta, Yoichi, Yamaguchi-Kabata, Yumi, Furuse, Tamio, Wakana, Shigeharu, Shimura, Takuya, Kobayashi, Rika, Shinoda, Yo, Goitsuka, Ryo, Maezawa, So, Sadakata, Tetsushi, Sano, Yoshitake, Furuichi, Teiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676974/
https://www.ncbi.nlm.nih.gov/pubmed/36419930
http://dx.doi.org/10.3389/fmolb.2022.1040237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676974/
https://www.ncbi.nlm.nih.gov/pubmed/36419930
http://dx.doi.org/10.3389/fmolb.2022.1040237

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