Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs

The most commonly used markers to assess complement activation are split products that are produced through activation of all three pathways and are located downstream of C3. In contrast, C4d derives from the cleavage of C4 and indicates either classical (CP) or lectin pathway (LP) activation. Altho...

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Detalles Bibliográficos
Autores principales: Hurler, Lisa, Toonen, Erik J. M., Kajdácsi, Erika, van Bree, Bregje, Brandwijk, Ricardo J. M. G. E., de Bruin, Wieke, Lyons, Paul A., Bergamaschi, Laura, Sinkovits, György, Cervenak, László, Würzner, Reinhard, Prohászka, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677118/
https://www.ncbi.nlm.nih.gov/pubmed/36420270
http://dx.doi.org/10.3389/fimmu.2022.1039765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677118/
https://www.ncbi.nlm.nih.gov/pubmed/36420270
http://dx.doi.org/10.3389/fimmu.2022.1039765

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