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Dendritic cell-specific transmembrane protein is required for synovitis and bone resorption in inflammatory arthritis

OBJECTIVE: Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) is essential for the formation of fully functional multinucleated osteoclasts. DC-STAMP deficient mice, under physiological conditions, exhibit osteopetrosis and develop systemic autoimmunity with age. However, the function of DC-ST...

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Detalles Bibliográficos
Autores principales: Garcia-Hernandez, Maria de la Luz, Rangel-Moreno, Javier, Garcia-Castaneda, Maricela, Kenney, H. Mark, Paine, Ananta, Thullen, Michael, Anandarajah, Allen P., Schwarz, Edward M., Dirksen, Robert T., Ritchlin, Christopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677122/
https://www.ncbi.nlm.nih.gov/pubmed/36420272
http://dx.doi.org/10.3389/fimmu.2022.1026574