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A Cre-driver rat model for anatomical and functional analysis of glucagon (Gcg)-expressing cells in the brain and periphery()

OBJECTIVE: The glucagon gene (Gcg) encodes preproglucagon, which is cleaved to form glucagon-like peptide 1 (GLP1) and other mature signaling molecules implicated in metabolic functions. To date there are no transgenic rat models available for precise manipulation of GLP1-expressing cells in the bra...

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Detalles Bibliográficos
Autores principales: Zheng, Huiyuan, López-Ferreras, Lorena, Krieger, Jean-Phillipe, Fasul, Stephen, Cea Salazar, Valentina, Valderrama Pena, Natalia, Skibicka, Karolina P., Rinaman, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677222/
https://www.ncbi.nlm.nih.gov/pubmed/36368622
http://dx.doi.org/10.1016/j.molmet.2022.101631