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Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells

Patients with glioblastoma (GBM) face a dismal prognosis. GBMs are driven by glioblastoma stem cells (GSCs) that display a neural stem cell (NSC)-like phenotype. These glioblastoma stem cells are often in a quiescent state that evades current therapies, namely debulking surgery and chemo/radiotherap...

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Detalles Bibliográficos
Autores principales: Ferguson, Kirsty M., Blin, Carla, Alfazema, Neza, Gangoso, Ester, Pollard, Steven M., Marques-Torrejon, Maria Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677454/
https://www.ncbi.nlm.nih.gov/pubmed/36420140
http://dx.doi.org/10.3389/fcell.2022.983097