Cargando…

How does the structure of data impact cell–cell similarity? Evaluating how structural properties influence the performance of proximity metrics in single cell RNA-seq data

Accurately identifying cell-populations is paramount to the quality of downstream analyses and overall interpretations of single-cell RNA-seq (scRNA-seq) datasets but remains a challenge. The quality of single-cell clustering depends on the proximity metric used to generate cell-to-cell distances. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Watson, Ebony Rose, Mora, Ariane, Taherian Fard, Atefeh, Mar, Jessica Cara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677483/
https://www.ncbi.nlm.nih.gov/pubmed/36151725
http://dx.doi.org/10.1093/bib/bbac387