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Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam
Most polygenic risk score (PRS)models have been based on data from populations of European origins (accounting for the majority of the large genomics datasets, e.g. >78% in the UK Biobank and >85% in the GTEx project). Although several large-scale Asian biobanks were initiated (e.g. Japanese,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677487/ https://www.ncbi.nlm.nih.gov/pubmed/36326078 http://dx.doi.org/10.1093/bib/bbac459 |