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Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam

Most polygenic risk score (PRS)models have been based on data from populations of European origins (accounting for the majority of the large genomics datasets, e.g. >78% in the UK Biobank and >85% in the GTEx project). Although several large-scale Asian biobanks were initiated (e.g. Japanese,...

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Detalles Bibliográficos
Autores principales: Pham, Duy, Truong, Buu, Tran, Khai, Ni, Guiyan, Nguyen, Dat, Tran, Trang T H, Tran, Mai H, Nguyen Thuy, Duong, Vo, Nam S, Nguyen, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677487/
https://www.ncbi.nlm.nih.gov/pubmed/36326078
http://dx.doi.org/10.1093/bib/bbac459