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Integrating multi-omics summary data using a Mendelian randomization framework

Mendelian randomization is a versatile tool to identify the possible causal relationship between an omics biomarker and disease outcome using genetic variants as instrumental variables. A key theme is the prioritization of genes whose omics readouts can be used as predictors of the disease outcome t...

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Detalles Bibliográficos
Autores principales: Jin, Chong, Lee, Brian, Shen, Li, Long, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677504/
https://www.ncbi.nlm.nih.gov/pubmed/36094096
http://dx.doi.org/10.1093/bib/bbac376