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Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke

In addition to neuroprotective strategies, neuroregenerative processes could provide targets for stroke recovery. However, the upregulation of inhibitory chondroitin sulfate proteoglycans (CSPGs) impedes innate regenerative efforts. Here, we examine the regulatory role of PTPσ (a major proteoglycan...

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Detalles Bibliográficos
Autores principales: Luo, Fucheng, Wang, Jiapeng, Zhang, Zhen, You, Zhen, Bedolla, Alicia, Okwubido-Williams, FearGod, Huang, L. Frank, Silver, Jerry, Luo, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677607/
https://www.ncbi.nlm.nih.gov/pubmed/35905716
http://dx.doi.org/10.1016/j.celrep.2022.111137