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Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model

BACKGROUND: Three-dimensional (3D) cell culture has emerged as an alternative approach to 2D flat culture to model more accurately the phenotype of solid tissue in laboratories. Culturing cells in 3D more precisely recapitulates physiological conditions of tissues, as these cells reduce activities r...

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Detalles Bibliográficos
Autores principales: Stransky, Stephanie, Cutler, Ronald, Aguilan, Jennifer, Nieves, Edward, Sidoli, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677638/
https://www.ncbi.nlm.nih.gov/pubmed/36411440
http://dx.doi.org/10.1186/s13072-022-00470-7