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Reduced oxidative stress suppresses neurotoxicity in the Drosophila model of TAF15-associated proteinopathies
TATA-binding protein associated factor 15 (TAF15) is involved in the pathology of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Although TAF15 accumulates as cytoplasmic aggregates in neurons and the clearance of aggregates may be a therapeutic strategy for ALS, the underlyi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677661/ https://www.ncbi.nlm.nih.gov/pubmed/36411469 http://dx.doi.org/10.1186/s13041-022-00979-8 |