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Reduced oxidative stress suppresses neurotoxicity in the Drosophila model of TAF15-associated proteinopathies

TATA-binding protein associated factor 15 (TAF15) is involved in the pathology of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Although TAF15 accumulates as cytoplasmic aggregates in neurons and the clearance of aggregates may be a therapeutic strategy for ALS, the underlyi...

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Detalles Bibliográficos
Autores principales: Han, Yeo Jeong, Kim, Kiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677661/
https://www.ncbi.nlm.nih.gov/pubmed/36411469
http://dx.doi.org/10.1186/s13041-022-00979-8