PTEN overexpression and nuclear β-catenin stabilization promote morular differentiation through induction of epithelial–mesenchymal transition and cancer stem cell-like properties in endometrial carcinoma

BACKGROUND: Although a lack of functional PTEN contributes to tumorigenesis in a wide spectrum of human malignancies, little is known about the functional role of its overexpression in the tumors. The current study focused on PTEN overexpression in endometrial carcinoma (Em Ca). METHODS: The functio...

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Detalles Bibliográficos
Autores principales: Yokoi, Ako, Minami, Marina, Hashimura, Miki, Oguri, Yasuko, Matsumoto, Toshihide, Hasegawa, Yoshinori, Nakagawa, Mayu, Ishibashi, Yu, Ito, Takashi, Ohhigata, Kensuke, Harada, Youhei, Fukagawa, Naomi, Saegusa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677676/
https://www.ncbi.nlm.nih.gov/pubmed/36411429
http://dx.doi.org/10.1186/s12964-022-00999-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677676/
https://www.ncbi.nlm.nih.gov/pubmed/36411429
http://dx.doi.org/10.1186/s12964-022-00999-w

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