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OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis

BACKGROUND: Radioresistance is the primary cause of nasopharyngeal carcinoma (NPC) treatment failure. Previous studies have focused on the deficits in cellular apoptosis as a mechanism for radioresistance; however, additional potential death modes involved in modulating radiosensitivity of NPC have...

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Detalles Bibliográficos
Autores principales: Di, Muping, Miao, Jingjing, Pan, Qiuzhong, Wu, Zonglong, Chen, Boyu, Wang, Muru, Zhao, Jingjing, Huang, Huageng, Bai, Jiewen, Wang, Qijing, Tang, Yan, Li, Yongqiang, He, Jia, Xiang, Tong, Weng, Desheng, Wang, Lin, Xia, Jianchuan, Zhao, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677691/
https://www.ncbi.nlm.nih.gov/pubmed/36411454
http://dx.doi.org/10.1186/s13046-022-02533-9