RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug

Nanoparticles of different sizes formulated with unmodified RNA and Protamine differentially engage Toll-like Receptors (TLRs) and activate innate immune responses in vitro. Here, we report that similar differential immunostimulation that depends on the nanoparticle sizes is induced in vivo in wild...

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Detalles Bibliográficos
Autores principales: Jarzebska, Natalia Teresa, Tusup, Marina, Frei, Julia, Weiss, Tobias, Holzinger, Tim, Mellett, Mark, Diken, Mustafa, Bredl, Simon, Weller, Michael, Speck, Roberto F., Kündig, Thomas M., Sahin, Ugur, Pascolo, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677980/
https://www.ncbi.nlm.nih.gov/pubmed/36419823
http://dx.doi.org/10.1080/2162402X.2022.2147665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677980/
https://www.ncbi.nlm.nih.gov/pubmed/36419823
http://dx.doi.org/10.1080/2162402X.2022.2147665

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