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JMJD6 orchestrates a transcriptional program in favor of endocrine resistance in ER+ breast cancer cells

High expression of Jumonji domain containing protein 6 (JMJD6) is strongly associated with poor prognosis in estrogen receptor positive (ER+) breast cancer. We overexpressed JMJD6 in MCF7 cells (JOE cells) and performed RNA-seq analysis. 76% of differentially expressed genes (DEGs) overlapped with E...

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Detalles Bibliográficos
Autores principales: Das, Partha, Gupta, Aritra, Desai, Kartiki V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678079/
https://www.ncbi.nlm.nih.gov/pubmed/36419768
http://dx.doi.org/10.3389/fendo.2022.1028616