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A novel oncolytic virus induces a regional cytokine storm and safely eliminates malignant ascites of colon cancer
BACKGROUND: Given malignant ascites with a terrible prognosis and a unique immune microenvironment, our purpose is to evaluate whether oncolytic herpes simplex virus type 2(OH2) is able to safely eliminate ascites of colon cancer and through which specific mechanism it exerts antitumor immunity. MET...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678102/ https://www.ncbi.nlm.nih.gov/pubmed/35510373 http://dx.doi.org/10.1002/cam4.4772 |