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A novel oncolytic virus induces a regional cytokine storm and safely eliminates malignant ascites of colon cancer

BACKGROUND: Given malignant ascites with a terrible prognosis and a unique immune microenvironment, our purpose is to evaluate whether oncolytic herpes simplex virus type 2(OH2) is able to safely eliminate ascites of colon cancer and through which specific mechanism it exerts antitumor immunity. MET...

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Detalles Bibliográficos
Autores principales:	Dong, Shuang, Liu, Binlei, Hu, Sheng, Guo, Fang, Zhong, Yi, Cai, Qian, Zhang, Siqi, Qian, Yu, Wang, Jun, Zhou, Fuxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678102/ https://www.ncbi.nlm.nih.gov/pubmed/35510373 http://dx.doi.org/10.1002/cam4.4772

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