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Molecular and clinical characteristics of IDH mutations in Chinese NSCLC patients and potential treatment strategies

BACKGROUND: Isocitrate dehydrogenase (IDH) is an appealing target for anticancer therapy, and IDH (IDH1/2) inhibitors have been approved for targeted therapy of acute myeloid leukemia (AML) and Cholangiocarcinoma. The therapeutic potential of IDH inhibitors for non‐small‐cell lung cancer (NSCLC) pat...

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Detalles Bibliográficos
Autores principales: Chen, Shuchen, Zhu, Honglin, Jin, Meizi, Yuan, Hongling, Liu, Zhenzhen, Li, Jielin, Zhang, Xiang, Meng, Lihui, Li, Ting, Diao, Yuzhu, Gao, Hong, Hong, Chengyu, Zhu, Xinjiang, Zheng, Jian, Li, Fei, Niu, Yanling, Ma, Tonghui, Li, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678110/
https://www.ncbi.nlm.nih.gov/pubmed/35526267
http://dx.doi.org/10.1002/cam4.4764