Papain ameliorates monocyte-platelet aggregate formation-mediated inflammatory responses in monocytes by upregulating miRNA-146a transcription

BACKGROUND: MicroRNA-146a (miRNA-146a) is a nuclear factor κB (NF-κB)-inducible and inflammation-sensitive miRNA, while papain elicits anti-inflammatory effects by inhibiting monocyte-platelet aggregate (MPA)-mediated NF-κB pathway activation in monocytes. This study aimed to demonstrate the underly...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Xu, Chan, Zhao, Yan, Huang, Qinghua, Yuan, Wufeng, Wu, Yan, Fei, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678272/
https://www.ncbi.nlm.nih.gov/pubmed/36409752
http://dx.doi.org/10.1371/journal.pone.0278059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678272/
https://www.ncbi.nlm.nih.gov/pubmed/36409752
http://dx.doi.org/10.1371/journal.pone.0278059

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