Cargando…

Papain ameliorates monocyte-platelet aggregate formation-mediated inflammatory responses in monocytes by upregulating miRNA-146a transcription

BACKGROUND: MicroRNA-146a (miRNA-146a) is a nuclear factor κB (NF-κB)-inducible and inflammation-sensitive miRNA, while papain elicits anti-inflammatory effects by inhibiting monocyte-platelet aggregate (MPA)-mediated NF-κB pathway activation in monocytes. This study aimed to demonstrate the underly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Lei, Xu, Chan, Zhao, Yan, Huang, Qinghua, Yuan, Wufeng, Wu, Yan, Fei, Xianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678272/ https://www.ncbi.nlm.nih.gov/pubmed/36409752 http://dx.doi.org/10.1371/journal.pone.0278059

Ejemplares similares

Papain Ameliorates the MPAs Formation-Mediated Activation of Monocytes by Inhibiting Cox-2 Expression via Regulating the MAPKs and PI3K/Akt Signal Pathway
por: Fei, Xianming, et al.
Publicado: (2018)

Platelet-monocyte aggregates: molecular mediators of thromboinflammation
por: Rolling, Christina C., et al.
Publicado: (2023)

Detection of Platelet-Monocyte Aggregates by the ADAM(® )Image Cytometer
por: Jung, Bo Kyeung, et al.
Publicado: (2014)

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
por: Hottz, Eugenio D., et al.
Publicado: (2020)

Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation
por: Vinci, Ramona, et al.
Publicado: (2021)

First Report of Elevated Monocyte-Platelet Aggregates in Healthy Children
por: Yip, Christina, et al.
Publicado: (2013)

Effect of PSI‐697, a Novel P‐Selectin Inhibitor, on Platelet–Monocyte Aggregate Formation in Humans
por: Japp, Alan G., et al.
Publicado: (2013)

Variation in Dietary Salt Intake Induces Coordinated Dynamics of Monocyte Subsets and Monocyte-Platelet Aggregates in Humans: Implications in End Organ Inflammation
por: Zhou, Xin, et al.
Publicado: (2013)

Increased platelet activation and lower platelet-monocyte aggregates in COVID-19 patients with severe pneumonia
por: Srihirun, Sirada, et al.
Publicado: (2023)

Platelets Promote Brucella abortus Monocyte Invasion by Establishing Complexes With Monocytes
por: Trotta, Aldana, et al.
Publicado: (2018)

Platelet-Monocyte Aggregates and C-Reactive Protein are Associated with VTE in Older Surgical Patients
por: Shih, Lauren, et al.
Publicado: (2016)

Relationship between monocyte‐platelet aggregation and endothelial function in middle‐aged and elderly adults
por: Haynes, Andrew, et al.
Publicado: (2017)

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
por: Oggero, Silvia, et al.
Publicado: (2021)

Lesion of Aggregated Monocytes and Mesothelial Cells: Mesothelial/Monocytic Incidental Cardiac Lesion
por: Erinanç, Hilal, et al.
Publicado: (2013)

The Kinetics of Circulating Monocyte Subsets and Monocyte-Platelet Aggregates in the Acute Phase of ST-Elevation Myocardial Infarction: Associations with 2-Year Cardiovascular Events
por: Zhou, Xin, et al.
Publicado: (2016)

Co-culture of Platelets with Monocytes Induced M2 Macrophage Polarization and Formation of Foam Cells: Shedding Light on the Crucial Role of Platelets in Monocyte Differentiation
por: Mehrpouri, Mahdieh, et al.
Publicado: (2019)

Monocyte-Platelet Interaction Induces a Pro-Inflammatory Phenotype in Circulating Monocytes
por: Passacquale, Gabriella, et al.
Publicado: (2011)

Evaluation of monocyte to high-density lipoprotein ratio, lymphocytes, monocytes, and platelets in psoriasis()()
por: Aktaş Karabay, Ezgi, et al.
Publicado: (2020)

Pathway Interaction Network Analysis Identifies Dysregulated Pathways in Human Monocytes Infected by Listeria monocytogenes
por: Fan, Wufeng, et al.
Publicado: (2017)

Monocyte–lymphocyte ratio is a valuable predictor for diabetic nephropathy in patients with type 2 diabetes
por: Huang, Qinghua, et al.
Publicado: (2020)

EphA receptors and ephrin-A ligands are upregulated by monocytic differentiation/maturation and promote cell adhesion and protrusion formation in HL60 monocytes
por: Mukai, Midori, et al.
Publicado: (2017)

Clinical and predictive significance of Plasma Fibrinogen Concentrations combined Monocyte-lymphocyte ratio in patients with Diabetic Retinopathy
por: Huang, Qinghua, et al.
Publicado: (2021)

Adaptive Immune Response Signaling Is Suppressed in Ly6C(high) Monocyte but Upregulated in Monocyte Subsets of ApoE (-/-) Mice — Functional Implication in Atherosclerosis
por: Yang, Pingping, et al.
Publicado: (2021)

The value of a new prognostic model developed by lymphocyte-monocyte ratio and platelet-monocyte ratio in peripheral T-cell lymphoma
por: Zhang, Yan, et al.
Publicado: (2021)

Reconstruction of Monocyte Transcriptional Regulatory Network Accompanies Monocytic Functions in Human Fibroblasts
por: Suzuki, Takahiro, et al.
Publicado: (2012)

Monocyte miRNAs Are Associated With Type 2 Diabetes
por: Parker, Daniel C., et al.
Publicado: (2022)

Human monocytes are associated with the formation of fibrin
Publicado: (1983)

Granulocyte and monocyte adsorptive apheresis ameliorates sepsis in rats
por: Ma, Shuai, et al.
Publicado: (2017)

Thromboxane generation by human monocytes enhances platelet function
Publicado: (1986)

Platelets and Smooth Muscle Cells Affecting the Differentiation of Monocytes
por: Williams, Michelle W. Y., et al.
Publicado: (2014)

Impaired Glucose Tolerance is Associated with Enhanced Platelet-Monocyte Aggregation in Short-Term High-Fat Diet-Fed Mice
por: Mkandla, Zibusiso, et al.
Publicado: (2019)

Monocyte-Derived miRNA-1914-5p Attenuates IL-1β–Induced Monocyte Adhesion and Transmigration
por: Toriuchi, Kohki, et al.
Publicado: (2023)

The Role of miRNA in Regulating the Fate of Monocytes in Health and Cancer
por: Alwani, Anna, et al.
Publicado: (2022)

Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
por: Naranbhai, Vivek, et al.
Publicado: (2015)

IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells
por: Rasouli, Javad, et al.
Publicado: (2021)

Absence of platelet membrane glycoproteins IIb/IIIa from monocytes
Publicado: (1985)

Monocytes complexed to platelets differentiate into functionally deficient dendritic cells
por: Singh, Meera V., et al.
Publicado: (2020)

Different Contribution of Monocyte- and Platelet-Derived Microvesicles to Endothelial Behavior
por: Brambilla, Marta, et al.
Publicado: (2022)

Monocyte-Platelet Aggregates Triggered by CD31 Molecule in Non-ST Elevation Myocardial Infarction: Clinical Implications in Plaque Rupture
por: Vinci, Ramona, et al.
Publicado: (2022)

Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia
por: La Rose, Anouk M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_71t4qf0mhcev13jeipa293tc2o