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DR4/DQ2 haplotype confers susceptibility to T1DM with early clinical disease onset: A retrospective analysis in a tertiary-care hospital in Italy

INTRODUCTION: T1DM is the most frequent form of diabetes in children. It has a multifactorial pathogenesis in which genetic, environmental and immunological factors are involved. Among genetic explanations a major role is attributed to second class HLA genes, with the greatest risk associated with t...

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Detalles Bibliográficos
Autores principales: Ricci, Silvia, Perugia, Francesca, Piccini, Barbara, Lodi, Lorenzo, Pegoraro, Francesco, Giovannini, Mattia, Rombolà, Giovanni, Perferi, Giancarlo, Toni, Sonia, Azzari, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678300/
https://www.ncbi.nlm.nih.gov/pubmed/36409706
http://dx.doi.org/10.1371/journal.pone.0276896