Modeling single-cell phenotypes links yeast stress acclimation to transcriptional repression and pre-stress cellular states

Stress defense and cell growth are inversely related in bulk culture analyses; however, these studies miss substantial cell-to-cell heterogeneity, thus obscuring true phenotypic relationships. Here, we devised a microfluidics system to characterize multiple phenotypes in single yeast cells over time...

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Detalles Bibliográficos
Autores principales: Bergen, Andrew C, Kocik, Rachel A, Hose, James, McClean, Megan N, Gasch, Audrey P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678356/
https://www.ncbi.nlm.nih.gov/pubmed/36350693
http://dx.doi.org/10.7554/eLife.82017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678356/
https://www.ncbi.nlm.nih.gov/pubmed/36350693
http://dx.doi.org/10.7554/eLife.82017

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