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Modeling single-cell phenotypes links yeast stress acclimation to transcriptional repression and pre-stress cellular states
Stress defense and cell growth are inversely related in bulk culture analyses; however, these studies miss substantial cell-to-cell heterogeneity, thus obscuring true phenotypic relationships. Here, we devised a microfluidics system to characterize multiple phenotypes in single yeast cells over time...
Autores principales: | Bergen, Andrew C, Kocik, Rachel A, Hose, James, McClean, Megan N, Gasch, Audrey P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678356/ https://www.ncbi.nlm.nih.gov/pubmed/36350693 http://dx.doi.org/10.7554/eLife.82017 |
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