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Smad3 promotes adverse cardiovascular remodeling and dysfunction in doxorubicin-treated hearts

Many anticancer therapies cause serious cardiovascular complications that degrade quality of life and cause early mortality in treated patients. Specifically, doxorubicin is known as an effective anticancer agent that causes cardiomyopathy in treated patients. There has been growing interest in defi...

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Detalles Bibliográficos
Autores principales: Cobb, Melissa S., Tao, Shixin, Shortt, Katherine, Girgis, Magdy, Hauptman, Jeryl, Schriewer, Jill, Chin, Zaphrirah, Dorfman, Edward, Campbell, Kyle, Heruth, Daniel P., Shohet, Ralph V., Dawn, Buddhadeb, Konorev, Eugene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678413/
https://www.ncbi.nlm.nih.gov/pubmed/36269647
http://dx.doi.org/10.1152/ajpheart.00312.2022