Cell-free DNA methylation-defined prognostic subgroups in small-cell lung cancer identified by leukocyte methylation subtraction

Small-cell lung cancer (SCLC) methylome is understudied. Here, we comprehensively profile SCLC using cell-free methylated DNA immunoprecipitation followed by sequencing (cfMeDIP-seq). Cell-free DNA (cfDNA) from plasma of 74 patients with SCLC pre-treatment and from 20 non-cancer participants, genomi...

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Detalles Bibliográficos
Autores principales: Ul Haq, Sami, Schmid, Sabine, Aparnathi, Mansi K., Hueniken, Katrina, Zhan, Luna Jia, Sacdalan, Danielle, Li, Janice J.N., Meti, Nicholas, Patel, Devalben, Cheng, Dangxiao, Philip, Vivek, Tsao, Ming S., Cabanero, Michael, de Carvalho, Daniel, Liu, Geoffrey, Bratman, Scott V., Lok, Benjamin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678731/
https://www.ncbi.nlm.nih.gov/pubmed/36425756
http://dx.doi.org/10.1016/j.isci.2022.105487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678731/
https://www.ncbi.nlm.nih.gov/pubmed/36425756
http://dx.doi.org/10.1016/j.isci.2022.105487

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