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Histone-like nucleoid structuring (H-NS) protein silences the beta-glucoside (bgl) utilization operon in Escherichia coli by forming a DNA loop

The bgl operon of Escherichia coli encodes proteins mediating the metabolism of aromatic beta-glucosides, but the operon is silent in wild type cells. Insertion of an insertion sequence (IS) element in the regulatory region upstream of the bgl promoter activates expression of the operon. The repress...

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Detalles Bibliográficos
Autores principales: Lam, Katie Jing Kay, Zhang, Zhongge, Saier, Milton H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678765/
https://www.ncbi.nlm.nih.gov/pubmed/36420159
http://dx.doi.org/10.1016/j.csbj.2022.11.027