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Anti-obesity effects of the dual-active adenosine A(2A)/A(3) receptor-ligand LJ-4378

BACKGROUND AND OBJECTIVES: A(2A) adenosine receptor (A(2A)AR)-mediated signaling in adipose tissues has been investigated as a potential target for obesity-related metabolic diseases. LJ-4378 has been developed as a dual-acting ligand with A(2A)AR agonist and A(3) adenosine receptor (A(3)AR) antagon...

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Detalles Bibliográficos
Autores principales: Kim, Kyungmin, Im, Hyeonyeong, Son, Yeonho, Kim, Minjae, Tripathi, Sushil Kumar, Jeong, Lak Shin, Lee, Yun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678795/
https://www.ncbi.nlm.nih.gov/pubmed/36167764
http://dx.doi.org/10.1038/s41366-022-01224-x