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Anti-obesity effects of the dual-active adenosine A(2A)/A(3) receptor-ligand LJ-4378
BACKGROUND AND OBJECTIVES: A(2A) adenosine receptor (A(2A)AR)-mediated signaling in adipose tissues has been investigated as a potential target for obesity-related metabolic diseases. LJ-4378 has been developed as a dual-acting ligand with A(2A)AR agonist and A(3) adenosine receptor (A(3)AR) antagon...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678795/ https://www.ncbi.nlm.nih.gov/pubmed/36167764 http://dx.doi.org/10.1038/s41366-022-01224-x |