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Establishment of a digital PCR method for detection of Borrelia burgdorferi sensu lato complex DNA in cerebrospinal fluid

Direct detection of Borrelia burgdorferi sensu lato bacteria in patient samples for diagnosis of Lyme neuroborreliosis (LNB) is hampered by low diagnostic sensitivity, due to few bacteria in cerebrospinal fluids (CSF) samples. Evaluation of novel molecular methods, including digital PCR (dPCR), as f...

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Detalles Bibliográficos
Autores principales: Leth, Trine Andreasen, Joensen, Sara Moeslund, Bek-Thomsen, Malene, Møller, Jens Kjølseth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678864/
https://www.ncbi.nlm.nih.gov/pubmed/36411296
http://dx.doi.org/10.1038/s41598-022-24041-8